The aim of this study was to screen various solvent extracts of whole plant of torilis leptophylla to display potent antioxidant activity in vitro and in vivo, total phenolic and flavonoid contents in order to find possible sources for future novel antioxidants in food and pharmaceutical formulations. Some of these plants rasayana have already been reported to possess strong antioxidant activity scartezzini and speroni, 2000. Antioxidant and antibacterial activities of ethanol. The antibacterial effect of some medicinal plant extracts and their synergistic effect with antibiotic and nonantibiotic drugs by mohamed mahmoud jouda supervisors a thesis submitted in partial fulfillment of the requirements for the degree of master in biological science microbiology 20. They found literally thousands of phytochemicals from plants as safe and broadly effective alternatives with less adverse effect.
Witch hazel, propolis epid, artichoke, and hawthorn afforded. Evaluation of antioxidant activity of medicinal plant. Analysis of selected medicinal plants as antioxidants with therapeutic potential for treating. A thesis submitted to fulfil the requirements for the degree of. Antioxidant activities of coumarins from korean medicinal. Effect of extraction solventtechnique on the antioxidant. In contrast, the sugar moiety markedly reduced the activities of coumarin glycosides. Acetylcholinesterase, alzheimer, antioxidant, antilipidperoxidation, medicinal plants introduction the investigation of plants used as remedies in traditional folk medicine can be as useful tool to identify several biologically active molecules from the 250 000 higher plant species testai, et. Phytochemical investigation and in vitro antioxidant.
Medicinal plants, traditional uses, phytochemical effects, antimicrobial activity. Several indian medicinal plants rasayana have been extensively used in the indian traditional ayurveda system of medicine for the management of neurodegenerative diseases mentioned earlier. Cet will be the subject of our second part of the thesis. Screening of medicinal plant extracts for antioxidant activity. Implications for alzheimers disease therapy by salam yousef jamil abu zaitoun supervisor dr. Estimation of phytochemical content and antioxidant. According to ayurveda, varied medicinal properties are attributed to different parts of mango. The antioxidative activity of a total of 92 phenolic extracts from edible and nonedible plant materials berries, fruits, vegetables, herbs, cereals, tree materials, plant sprouts, and seeds was examined by autoxidation of methyl linoleate. Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives. Green tea, oligomeric procyanidins from grape seed and pine bark, bilberry, and ginkgo exhibited taa in the range of 5.
Investigation of traditional australian aboriginal and. A large number of medicinal plants and their purified constituents have shown beneficial therapeutic potentials. A study of antimicrobial activity of few medicinal herbs parastoo karimi alavijeh, parisa karimi alavijeh and devindra sharma j. Screening of in vitro antioxidant activity of methanolic leaf. Medicinal plants with antiinflammatory activities from. Among these medicinal plants, apiaceae, lamiaceae, and boraginaceae were the most dominant families with 4, 2, 2 species belonging to 4, 2, 2 genera of medicinal plants, respectively. Different parameters studied include phenolic contents, moisture, ash, crude fiber, fats and waxes. Rich anacardiaceae and crossopteryx febrifuga afzel benth. The studied medicinal plants have interesting antioxidant properties, antibacterial activity and a phytochemicals composition that could provide scientific evidence for some folk uses in the treatment of diseases and therefore it can provide natural source of antibacterial drugs and antioxidants and can be useful.
Antioxidant properties of extracts from selected plant materials caesalpinia spinosa, perilla frutescens, artemisia annua and viola wittrockiana. Antioxidant properties have been attributed to the essential oils but a great diversity of results has been reported, mainly attributed to the chemical composition of the essential oils and the diversity of tests used. Berit smestad paulsen department of pharmaceutical chemistry, institute of pharmacy. Several medicinal plants rasayana have also been extensively used in the indian traditional ayurveda system of medicine for the treatment of number of diseases18. Ficus racemosa, antioxidant activity, antibacterial activity, cytotoxic activity, dpph, abts, xttassay. Some indian traditional medicinal plants w ith antioxidant. Pdf final accepted version with authors formatting. Methods in vitro antioxidant activity was evaluated by studying 1,1diphenyl2picrylhydrazyl. Antioxidant properties of extracts from selected plant materials.
The purpose of this thesis is to investigate a small selection of medicinal plants. Results a total of 94 plant species from 41 families were reported to be used as medicinal plants in. Some of these plants have shown potent antioxidant activity16,7. Master of science honours school of science and health. Celery apium graveolens l is a plant from the apiaceae family and phenolic and antioxidant compounds of this plant have been studied by several scientists. Isolation and characterisation of medicinal compounds from 19 dec 20 isolation and characterisation of medicinal phd thesis. Some turkish medicinal plants with antimicrobial avtivities. Libyan capparis spinose has good antioxidant activity. Similarly in the entire concentration of methanol extract of the plant, the seed had highest antioxidant activity. A detailed study was performed on the antioxidant activity of the methanol extract of whole. Antioxidant activity and phenolic content of some medicinal. Phytochemical investigation and in vitro antioxidant activity. The major plant compounds characterized by antioxidant activity are polyphenols. An ethnobotanical, antioxidant and antiinflammatory study.
Pdf a thesis for bachelors degree on phytochemical. Chinese medicinal plants contain a wide variety of natural antioxidants, such as phenolic acids, flavonoids and tannins and possess more potent antioxidant activity than common dietary plants cai et al. Medicinal plants used in the traditional medicine are wellknown significant sources of natural antioxidants. Analysis of selected medicinal plants as antioxidants with. A study of antimicrobial activity of few medicinal herbs. The traditional medicinal plants have the antidiabetic activity and it can lower the glucose levels in diabetic patients. Evaluation of in vitro antioxidant activity in the traditional medicinal shrub of. Antioxidant activity in medicinal plants associated with the. To study the invitro and invivo antioxidant properties of some common plant. Extract, free radical, antioxidant activity, medicinal plant. Introduction medicinal plants are abundant source of antimicrobial molecules. Antioxidant and antibacterial activities of ethanol extract and.
Study of the antioxidant activity of phenolic extracts of a. Antioxidant activity, total phenolic and total flavonoid. Nitric oxide scavenging activity, antioxidant activity, active nitrogen species, sodium nitroprusside. Keeping the above in view the present chapter focuses on the i diversity of antioxidant phytochemicals in medicinal. Antioxidant activity of medicinal and aromatic plants. Effect of extraction solventtechnique on the antioxidant activity of selected medicinal plant extracts bushra sultana 1, farooq anwar 1, and muhammad ashraf 2 1 department of chemistry and biochemistry, university of agriculture, faisalabad38040, pakistan 2 department of botany, university of agriculture, faisalabad38040, pakistan. A wide range of medicinal plants extracts are used to treat several infections as they have potential antimicrobial activity. Natural products have been rediscovered as important tools for drug development despite advances in combinatorial chemistry. I hereby declare that the dissertationthesis submitted for m tech. The study showed that the plant revealed an antioxidant activity 80% with ic 50 0. Antibacterial and antioxidant activities of 8 aromatic plants from the balkan peninsula were studied. Results showed that both of ethanolic and water extracts of some plant possessed high cytotoxic and antioxidant activities and inhibited the cell growth of cancer cells.
Introduction of medicinal plants species with the most. The antioxidant activity of these two medicinal plants was evaluated by measuring reducing ability, free radical scavenging activity by dpph and hydrogen peroxide methods. Torilis leptophylla belonging to the apiaceae family 14 or more commonly known as bristle fruit hedge parsley, is a forb of the genus torilis, distributed in asia, europe and north africa. Antibacterial activity in vitro of medicinal plants wardah shahid 1, rabia durrani 2, saira iram2, maryam durrani 3, fawad ali khan 4 1plant taxonomy lab, department of plant sciences, faculty of biological sciences, quaidiazam university, 45320, 00925190643194, islamabad, pakistan.
The findings suggested that the selected medicinal plants have a promising potential to cure ailments and maintain a healthy life and should be investigated further to determine the components responsible for activity. Objective to evaluate the antioxidant capability of the methanolic leaf extract of acalypha fruticosa. Evaluating medicinal plants for anticancer activity. Pdf methods for determining the antioxidant activity. An ethnobotanical, antioxidant and antiinflammatory study of. Minimal bactericidal concentration of metanoic extracts ranged from 12. Acetylcholinesterase inhibition and antioxidant activity. Pdf traditional medicinal plants research in egypt. Antioxidant activity of some common medicinal plants. Rhizophora mangle is a plant from rhizophoraceae family.
Complement fixing polysaccharides from chinese medicinal plant codonopsis pilosula yuanfeng zou thesis submitted for the degree of ph. Wine has been recognized for its antioxidant activity kinsella et al. Plants contain phytochemicals with various bioactivities including antioxidant. Passiflora foetida is a traditional medicinal plant, it have many. The wine we tested had significantly lower free radical activity than 86% of the medicinal plants tested with 20% of the plants also higher in superoxide scavenging. Submit your instructions to our writers for free by filling our simple order form. The assays employed were ferric reducing antioxidant power, trolox equivalent antioxidant. Minimal inhibitory concentration of metanoic extracts ranged from 6. Journal of medicinal plant research vol 624pp 40824086 26 june, 2012. Invitro evaluation of acetylcholinesterase inhibition and. Paulsenantioxidant and 15lipoxygenase inhibitory activities of the malian medicinal plants diospyros abyssinica hiern f.
Gangavaram maheshwar reddy,visweswaran rao dolly sarma etal evaluation of antioxident activity index by the 2,2 diphenyl 1 picryl hydrazyl method of 40 medicinal plants. The most common and widely distributed group of phenolic compounds in plants is flavonoids. Medicinal plants derived natural antioxidants, which are in the form of raw extracts andor chemical constituents, are very efficient to block the process of oxidation by neutralizing free radicals 3. Recently there has been an upsurge of interest in the therapeutic potential of medicinal plants as antioxidants in reducing such free radicals, induced injury pourmorad etal. Abstract identification and characterization of natural products with antioxidant and antiproliferative activity has received much interest over the past few years. Phytoconstituents derived from the herbs of cedrus deodara, piper longum, picrorhiza kurroa, berberis aristata, vitex negundo linn, etc. The powder samples and methanol extract of 11 medicinal plants were subjected to analysis of proximate composition and measurement of antioxidant activity. Study of total phenolic and flavonoid content, antioxidant. Effect of drying on the phenolic content and the antioxidant activity of. The use of medicinal plants with high level of antioxidant constituents has been proposed as an effective therapeutic approach for hepatic damages. The bark extract of the plant showed scavenging activity of hydroxyl radicals and the extract contained polyphenols, carbohydrates and sterols4. The antioxidants compounds like ascorbic acid, total phenols and tannins were also evaluated in these plants. The medicinal plants used in traditional medicine are particularly interesting for the study of their antioxidant activity. Plants contain a wide variety of free radical scavenging molecules, such as polyphenols, dietary glutathione, vitamins and endogenous metabolites.
Antibacterial and antioxidant activity of traditional. Commonly used medicinal plant extracts with standardized content of polyphenols were investigated for their total antioxidant activity taa. Extraction, isolation and characterization of bioactive. In the dry guava extract there were high levels of phenolics 766. Study of total phenolic and flavonoid content, antioxidant activity and antimicrobial properties of medicinal plants volume 1 issue 1 2014 sarabjot kaur,1 poonam mondal2 1department of pharmaceutical sciences, assam university, india 2department of biotechnology, lovely professional university, india. So the aim of the present study is to evaluate the dpph. Introduction experimental evidence suggests that free radicals and reactive oxygen spec ies ros can be involved in high number. The antioxidant activity of the 90 plant extracts was determined by 2, 2 diphenyl1picrylhydrazyl dpph assay. The antibacterial effect of some medicinal plant extracts and. Phytochemicals are extensively found at different levels in many medicinal plants. Antioxidant activity of some algerian medicinal plants. Evaluation of antioxidant activity of medicinal plant 885 figure 2. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext.
To study the in vitro and invivo antioxidant properties of some common plant. The aim of this study was to evaluate the antioxidant activity of selected nonfood plants, traditionally used. Mangoes belong to genus mangifera which consists of about 30 species of tropical fruiting trees in the flowering plant family anacardiaceae. Provide sufficient details and upload all relevant materials to help thesis on antioxidant activity of medicinal plants the writers determine what you need. Materials and methods chemicals and reagents dpph, gallic acid, 2,4,6tripyridylstriazine tptz, 6hydroxy2,5,7,8 tetramethyl. Invitro evaluation of acetylcholinesterase inhibition and antioxidant activity of selected palestinian medicinal plants. Mangifera indica mi, also known as mango, aam, it has been an important herb in the ayurvedic and indigenous medical systems for over 4000 years. A thesis for bachelors degree on phytochemical screening and analysis of antibacterial and antioxidant activity of ficus auriculata, lour. Phytochemical investigation and in vitro antioxidant activity of an. Anticancer activity of the selected medicinal plants.
Many of the natural products in plants of medicinal value offer us new sources of drugs. Comparative study of antioxidant properties and total. Pdf thesis antioxidant activity of amaranthus gangeticus. The antibacterial effect of some medicinal plant extracts and their synergistic effect with antibiotic and nonantibiotic drugs by mohamed mahmoud jouda supervisors a thesis submitted in partial fulfillment of the requirements for the degree of master in biological science microbiology 20 1434 dr. Of the 16 medicinal plants, 8 species had similar effects in traditional and medicinal uses. Plants have been used for medical purposes since the beginning of human history and are the basis of modern medicine.
Total phenolic content was also determined by the folin. It was observed that the ethanol phytofraction 1 mgml of all the tested plants showed promising anticancer activity toward the selected cancer cell lines. In vitro nitric oxide scavenging activity of methanol. Mericli thesis submitted in partial fulfillment of the requirements for the degree of. Introduction the many number of medicinal plants are used in the cellular and metabolic disease. Isolation and characterisation of biopolymers from anticancer medicinal herbs. The results of cytotoxicity of the selected plant samples ethanol extract against the selected cancer cells are summarized in table 1.
Evaluation of anticancer, antioxidant, and possible anti. Evaluation of antioxidant activity of two important memory. Introduction india is known for its rich diversity of medicinal plants and hence called botanical garden of the world 1. Pdf in vitro antioxidant and antiproliferative activity.
Our hypothesis was that whole plant extracts selected according to ethnobotanical sources of historical use might contain multiple molecules with. These plants exhibit strong antioxidant activity that can explain their uses in traditional medicines in the past as well as prese nt. The most practical way to fight degenerative diseases is to increase antioxidant activity in our body and that could be achieved by consumption of vegetables, fruits or edible plants. Medicinal plants with antiinflammatory activities from selected countries and regions of africa oluwafemi o oguntibeju phytomedicine and phytochemistry group, oxidative stress research centre, department of biomedical sciences, faculty of health and wellness sciences, cape peninsula university of technology, bellville, south africa abstract. Frap assay was done according to benzie and strain procedure 40.
A study has already been done on the antioxidant capacity of the roots of c. Phytochemicals screening and evaluation of antioxidants and. Antioxidant, antibacterial and antitumor activity of. Biological and chemical studies of medicinal plants a. Chemistry and biological activities of medicinal plants from mali b. Antioxidant properties of medicinal plants from peru. Ethiopia is one of the developing countries which have enormous diversity of plants. Diospyros malabarica is a plant from ebenaceae family. Free radical scavenging activity was evaluated using 1,1.
There is an increasing interest in natural antioxidants e. Antioxidant properties of several medicinal plants growing. All eight crude plant extracts showed marked antioxidant activity in both assays. The antioxidant activity of polyphenols is accredited to their redox properties i. The coumarins having a catechol group, 2, 3 and 19, showed significant free radical scavenging activity and inhibitory effects on lipid peroxidation, indicating that the catechol group significantly contributed to the antioxidant activities of coumarins. Aqueous extracts of 30 plants were investigated for their antioxidant properties using dpph and abts radical scavenging capacity assay, oxygen radical absorbance capacity orac assay, superoxide dismutase sod assay, and ferric reducing antioxidant potential frap assay. In fact, several in vitro assays for the determination of antioxidant ability have been used. However, due to having a large variety of medicinal plants species, all of the major medicinal plants have not yet been evaluated for their medicinal properties, including antioxidant activity.
Although a number of plants traditionally been used by the people of purulia district for the treatment of different diseases e. Plant phenolics are widely distributed in the tissues of plants as well as play a vital role in the highly effective free radical scavengers and antioxidant activity. Antioxidant activity of plant extracts containing phenolic. The antibacterial effect of some medicinal plant extracts.
Caffea arabica showed greater antioxidant activity measured as scavenging of dpph, superoxide radicals, reducing power and inhibition of microsomal lipid peroxidation. In vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from southern africa ea adewusi, v steenkamp department of pharmacology, school of medicine, faculty of health sciences, university of pretoria, south africa contents lists available at sciencedirect asian. However, majority of plants have not yet been screened for such activity. Traditional medicinal plants from zimbabwe for phytochemistry, antioxidant, antimicrobial, antiviral and toxicological activities by deniz iklim viol supervisor. Plants are an important source of natural active products that are different, based on mechanism and biological properties. Quantification of bioactive compounds and evaluation of the. Antibacterial activity in vitro of medicinal plants. It has been reported that the antioxidant activity of phenol is mainly due to their redox properties. Biological and chemical studies of medicinal plants.
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